Publications

2021

42. In vitro Efficacy of Artemisia Extracts Against SARS-CoV-2

Nie, C.; Trimpert, J.; Moon, S.; Haag, R.; Gilmore, K.; Kaufer, B. B.; Seeberger, P. H. BioRxiv. 2021, DOI: 10.1101/2021.02.14.431122. read it here

 

41. Combining Radial and Continuous Flow Synthesis to Optimize and Scale-up the Production of Medicines

Guidi, M.; Moon, S.; Anghileri, L.; Cambié, D.; Seeberger, P. H.; Gilmore, K. React. Chem. Eng. 2021, 6, 220-224. read it here

 

40. Predicting Glycosylation Stereoselectivity Using Machine Learning

Moon, S.; Chatterjee, S.; Seeberger, P. H.; Gilmore, K. Chem. Sci. 2021, DOI:10.1039/D0SC06222G (Edge Article). read it here

Original ChemRxiv publication:

ChemRxiv 2020, DOI: 10.26434/chemrxiv.12357302.v1. read it here

2020

39. In Vitro Efficacy of Artemisinin-Based Treatments Against SARS-CoV-2

Gilmore, K.; Zhou, Y.; Ramirez, S.; Pham, L. V.; Fahnoe, U.; Feng, S.; Offersgaard, A.; Trimpert, J.; Bukh, J.; Osterrieder, K.; Gottwein, J.; Seeberger, P. H. BioRxiv 2020, DOI:10.1101/2020.10.05.326637. read it here

 

38. How to Approach Flow Chemistry (Tutorial Review)

Guidi, M.; Seeberger, P. H.; Gilmore, K.  Chem. Soc. Rev. 2020, 49, 8910-8932. read it here

 

37. The Impact of Leaving Group Anomericity on the Structure of Glycosyl Cations of Protected Galactosides

Greis, K.; Mucha, E.; Lettow, M.; Thomas, D. A.; Kirschbaum, C.; Moon, S.; Pardo-Vargas, A.; von Helden, G.; Meijer, G.; Gilmore, K.; Seeberger, P. H.; Pagel, K. ChemPhysChem 2020, 21, 1905. read it here

 

36. Remote Participation During Glycosylation Reactions of Galactose Building Blocks: Direct Evidence From Cryogenic Vibrational Spectroscopy

Marianski, M.; Mucha, E.; Greis, K.; Moon, S.; Pardo, A.; Kirschbaum, C.; Thomas, D. A.; Meijer, G.; Helden, G. v.; Gilmore, K.; Seeberger, P. H.; Pagel, K. Angew. Chem. Int. Ed. 2020, 59, 6166-6172. read it here

 

35. Automated Radial Synthesis of Small Molecules

Chatterjee, S.; Guidi, M.; Seeberger, P. H.; Gilmore, K.  Nature 2020, 579, 379-384read it here

                    Highlighted by: Nature Views and NewsChemical and Engineering NewsChemistry World

 

2019

34. Energy-Efficient Solar Photochemistry using Photomicroreactors

Cambié, D.; Dobbelaar, J.; Paiva, P. R.; Vanderspikken, J.; Shen, C.; Seeberger, P. H.; Gilmore, K.; Debije, M. G.; Noel, T.  Angew. Chem. Int. Ed. 2019, 131, 14512-14516read it here 

 

33. Click, Zoom, Explore: Interactive 3D (i-3D) Figures in Standard Manuscript PDFs

Chatterjee, S.; Moon, S.; Rowlands, A.; Chin, F.; Seeberger, P. H.; Merbouh, N.; Gilmore, K. ChemRxiv 2019, DOI: 10.26434/chemrxiv.7701695read it here

                    Highlighted by: Chemistry World

 

2018

32. Palladium-Catalyzed Intramolecular Addition of Aryl Bromides to Aldehydes as Key to the Synthesis of 3,3-Dimethylchroman-4-ones and 3,3-Dimethylchroman-4-ols

Viana, H.; Marques, C. S.; Correa, C.; Gilmore, K.; Galvão, L.; Vieira, L.; Seeberger, P. H.; Burke, A. J.  ChemistrySelect 2018, 40, 11333-11338read it here

 

31. An Integrated Lab-on-a-Chip Approach to Study Heterogeneous Enantioselective Catalysis at the Microscale

Warias, R.; Zaghi, A.; Heiland, J. J.; Piendl, S. K.; Gilmore, K.; Seeberger, P. H.; Massi, A.; Belder, D. ChemCatChem 2018, 23, 5382-5385. read it here

 

30. An Empirical Understanding of the Glycosylation Reaction

Chatterjee, S.; Moon, S.; Hentschel, F.; Gilmore, K., Seeberger, P. H. J. Am. Chem. Soc. 2018, 140, 11942-11953read it here

 

29. Chemoselective Photoredox Synthesis of Unprotected Primary Amines Using Ammonia

Rong, J.; Seeberger, P. H.; Gilmore, K. Org. Lett. 2018, 20, 4081-4085. read it here

 

28. Literally Green Chemical Synthesis of Artemisinin from Plant Extracts

Trimer, S.; Gilmore, K.*; Vu, G. T.; Seeberger, P. H.; Seidel-Morgenstern, A. Angew. Chem. Int. Ed. 2018, 57, 5525-5528. read it here

                    Highlighted by: Chemical and Engineering NewsChemistry World

 

27. Continuous Heterogeneous Photocatalysis in Serial Micro-Batch Reactors

Pieber, B.; Shalom, M.; Antonietti, M.; Seeberger, P. H.; Gilmore, K. Angew. Chem. Int. Ed. 2018, 57, 9976-9979. read it here

 

2017

26.Integrated Flow Processing – Challenges in Continuous Multistep Synthesis (Invited Perspective)

Pieber, B.; Gilmore, K.; Seeberger, P. H.  J. Flow Chem. 2017, 7, 129-136. read it here

 

25. The Hitchhiker’s Guide to Flow Chemistry

Plutschack, M. B.; Pieber, B.; Gilmore, K.; Seeberger, P. H. Chem. Rev. 2017, 117, 11796-11893. read it here

 

24. Visible-Light-Mediated Achmatowicz Rearrangement

Plutschack, M. B.; Seeberger, P. H.; Gilmore, K. Org. Lett. 2017, 19, 30-33read it here

 

2016

23. Synthesis of α-Nitro Carbonyls via Nitrations in Flow

Chentsova, A.; Ushakov, D.; Seeberger, P. H.; Gilmore, K.  J. Org. Chem. 2016, 81, 9415-9421read it here

 

22. Integrated on-chip mass spectrometry reaction monitoring in microfluidic devices containing porous polymer monolithic columns

Dietze, C.; Schulze, S.; Ohla, S.; Gilmore, K.; Seeberger, P. H.; Belder, D.  Analyst 2016, 141, 5412-5416. read it here

 

21. A Sustainable, Semi-Continuous Flow Synthesis of Hydantoins

Vukelić, S.; Koksch, B.; Seeberger, P. H.; Gilmore, K. Chem. Eur. J. 2016, 22, 13451-13454. read it here

 

20. The Baldwin Rules: Revised and Extended (Invited Review)

Gilmore, K.; Mohamed, R. K.; Alabugin, I. V. WIREs, Comp. Mol. Sci. 2016, 6, 487-514. read it here

 

2015

19. Continuous and Convergent Access to Vicinyl Amino Alcohols

Nobuta, T.; Xiao, G.; Ghislieri, D.; Gilmore, K.; Seeberger, P. H. Chem. Commun. 2015, 51, 15133-15136. read it here

 

18. Flow Synthesis of Fluorinated α-Amino Acids

Vukelić, S.; Ushakov, D. B.; Gilmore, K.; Koksch, B.; Seeberger, P. H. Eur. J. Org. Chem. 2015, 14, 3036-3039. read it here

 

17. Recovery of Artemisinin from a Complex Reaction Mixture using Continuous Chromatography and Crystallization

Horváth, Z.; Horosanskaia, E.; Lee, J. W.; Lorenz, H.; Gilmore, K.; Seeberger, P. H.; Seidel-Morgenstern, A. Org. Process Res. Dev. 2015, 19, 624-634read it here

 

16.Factors Influencing the Regioselectivity of Asymmetric Secondary Amine Oxidation with Singlet Oxygen

Ushakov, D. B.; Plutschack, M. B.; Gilmore, K.; Seeberger, P. H. Chem. Eur. J. 2015, 21, 6528-6534. read it here

 

15. A Concise Flow Synthesis of Efavirenz

Correia, C. A.; Gilmore, K.; McQuade, D. T.; Seeberger, P. H. Angew. Chem. Int. Ed. 2015, 54, 4945-4948. read it here

 

14. Chemical Assembly Systems: Layered Control for Divergent, Continuous, Multi-Step Syntheses of APIs

Ghislieri, D.; Gilmore, K.; Seeberger, P. H. Angew. Chem. Int. Ed. 2015, 54, 678. read it here

 

2014

13. Continuous Reductions and Reductive Aminations Using Solid NaBH4

Gilmore, K.; Vukelić, S.; McQuade, D. T.; Koksch, B.; Seeberger, P. H. Org. Process Res. Dev. 2014, 18, 1771. read it here

                    Highlighted by: Chemical and Engineering News

 

12. Continuous Synthesis of Artemisinin-Derived Medicines

Gilmore, K.; Kopetzki, D.; Lee, J. W.; Horváth, Z.; McQuade, D. T.; Seidel-Morgenstern, A.; Seeberger, P. H. Chem. Commun. 2014, 50, 12652. read it here

Highlighted by: Chemistry World

 

11. Consecutive Oxygen-based Oxidations Convert Amines to α-cyanoepoxides

Ushakov, D. B.; Gilmore, K.; Seeberger, P. H. Chem. Commun. 2014, 50, 12649. read it here

 

10. Continuous Flow Photochemistry (Invited Personal Account)

Gilmore, K.; Seeberger, P. H. The Chemical Record 2014, 3, 410read it here

 

9. A Continuous Flow Oxidative Cyanation of Primary and Secondary Amines Using Singlet Oxygen

Ushakov, D. B.; Gilmore, K.; Kopetzki, D.; McQuade, D. T.; Seeberger, P. H. Angew. Chem. Int. Ed. 2014, 53, 557. read it here

 

2013

8. Finding the Right Path: Baldwin “Rules for Ring Closure” and Stereoelectronic Control of Cyclizations (Invited Viewpoint)

Alabugin, I. V.; Gilmore, K. Chem. Commun. 2013, 49, 11246. read it here

 

7. Convenient, Ambient Temperature Generation of Sulfonyl Radicals for Addition to Alkynes (Invited Paper)

Gilmore, K.; Gold, B.; Clark, R. J.; Alabugin, I. V.  Aus. J. Chem. 2013, 66, 336. read it here

 

2012

6. Aromatic Transition States in Nonpericyclic Reactions: Anionic 5-Endo Cyclizations Are Aborted Sigmatropic Shifts

Gilmore, K.; Manoharan, M.; Wu, J. I.-C.; Schleyer, P. v. R.; Alabugin, I. V. J. Am. Chem. Soc. 2012, 134, 10584. read it here

 

2011

5. Dissecting Alkynes: Full Cleavage of Polarized C≡C Moiety via Sequential bis-Michael Addition/Retro-Aldol Cascade

Roy, S.; Davydova, M. P.; Pal, R.; Gilmore, K.; Tolstikov, G. A.; Vasilevsky, S. F.; Alabugin, I. V.  J. Org. Chem. 2011, 76, 7482. read it here

 

4. Cyclizations of Alkynes: Revisiting Baldwin’s Rules for Ring Closure

Gilmore, K.; Alabugin, I. V. Chem. Rev. 2011, 111, 6513. read it here

 

3. Rules for Anionic and Radical Ring Closure of Alkynes

Alabugin, I. V.; Gilmore, K.; Manoharan, M. J. Am. Chem. Soc. 2011, 133, 12608. read it here

 

2. Hyperonjugation (Invited review)

Alabugin, I. V.; Gilmore, K. M.; Peterson, P. W. WIREs, Comp. Mol. Sci. 2011 1, 109-141. read it here

 

2008

1. Radical Cascade Transformations of Tris(o-aryleneethynylenes) into Substituted Benzo[a]indeno[2,1-c]fluorenes

Alabugin, I. V.; Gilmore, K.; Patil, S.; Manoharan, M.; Kovalenko, S. V.; Clark, R. J.; Ghiviriga, I. J. J. Am. Chem. Soc. 2008, 130, 11535. read it here